Running examples in ‘SeedMatchR-Ex.R’ failed
The error most likely occurred in:

> ### Name: plot_seeds
> ### Title: Plot the Guide Strand with different optional seeds
> ### Aliases: plot_seeds
> 
> ### ** Examples
> 
> library(msa)
Loading required package: Biostrings
Loading required package: BiocGenerics
Loading required package: generics

Attaching package: ‘generics’

The following objects are masked from ‘package:base’:

    as.difftime, as.factor, as.ordered, intersect, is.element, setdiff,
    setequal, union


Attaching package: ‘BiocGenerics’

The following objects are masked from ‘package:stats’:

    IQR, mad, sd, var, xtabs

The following objects are masked from ‘package:base’:

    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, is.unsorted, lapply,
    mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
    rank, rbind, rownames, sapply, saveRDS, table, tapply, unique,
    unsplit, which.max, which.min

Loading required package: S4Vectors
Loading required package: stats4

Attaching package: ‘S4Vectors’

The following object is masked from ‘package:utils’:

    findMatches

The following objects are masked from ‘package:base’:

    I, expand.grid, unname

Loading required package: IRanges
Loading required package: XVector
Loading required package: GenomeInfoDb

Attaching package: ‘Biostrings’

The following object is masked from ‘package:base’:

    strsplit

> 
> # Ttr siRNA sequence
> guide.seq = "UUAUAGAGCAAGAACACUGUUUU"
> 
> # generate seed plot
> plotted.seeds = plot_seeds(guide.seq)
use default substitution matrix
Error in dyn.load(file, DLLpath = DLLpath, ...) : 
  unable to load shared object '/data/gannet/ripley/R/test-dev/proj4/libs/proj4.so':
  libproj.so.22: cannot open shared object file: No such file or directory
Calls: plot_seeds ... namespaceImport -> loadNamespace -> library.dynam -> dyn.load
Execution halted