Error(s) in re-building vignettes:
  ...
--- re-building ‘PhenotypeSimulator.Rmd’ using rmarkdown
--- finished re-building ‘PhenotypeSimulator.Rmd’

--- re-building ‘Simulation-and-LinearModel.Rmd’ using rmarkdown
Could not fetch http://www.zotero.org/styles/plos
HttpExceptionRequest Request {
  host                 = "www.zotero.org"
  port                 = 80
  secure               = False
  requestHeaders       = []
  path                 = "/styles/plos"
  queryString          = ""
  method               = "GET"
  proxy                = Nothing
  rawBody              = False
  redirectCount        = 10
  responseTimeout      = ResponseTimeoutDefault
  requestVersion       = HTTP/1.1
  proxySecureMode      = ProxySecureWithConnect
}
 (InternalException (HandshakeFailed (Error_Protocol "peer does not support Extended Main Secret" HandshakeFailure)))
Error: processing vignette 'Simulation-and-LinearModel.Rmd' failed with diagnostics:
pandoc document conversion failed with error 61
--- failed re-building ‘Simulation-and-LinearModel.Rmd’

--- re-building ‘SimulationBasedOnExampleData.Rmd’ using rmarkdown
Could not fetch http://www.zotero.org/styles/plos
HttpExceptionRequest Request {
  host                 = "www.zotero.org"
  port                 = 80
  secure               = False
  requestHeaders       = []
  path                 = "/styles/plos"
  queryString          = ""
  method               = "GET"
  proxy                = Nothing
  rawBody              = False
  redirectCount        = 10
  responseTimeout      = ResponseTimeoutDefault
  requestVersion       = HTTP/1.1
  proxySecureMode      = ProxySecureWithConnect
}
 (InternalException (HandshakeFailed (Error_Protocol "peer does not support Extended Main Secret" HandshakeFailure)))
Error: processing vignette 'SimulationBasedOnExampleData.Rmd' failed with diagnostics:
pandoc document conversion failed with error 61
--- failed re-building ‘SimulationBasedOnExampleData.Rmd’

--- re-building ‘sample-scripts-external-genotype-simulation.Rmd’ using rmarkdown
Could not fetch http://www.zotero.org/styles/plos
HttpExceptionRequest Request {
  host                 = "www.zotero.org"
  port                 = 80
  secure               = False
  requestHeaders       = []
  path                 = "/styles/plos"
  queryString          = ""
  method               = "GET"
  proxy                = Nothing
  rawBody              = False
  redirectCount        = 10
  responseTimeout      = ResponseTimeoutDefault
  requestVersion       = HTTP/1.1
  proxySecureMode      = ProxySecureWithConnect
}
 (InternalException (HandshakeFailed (Error_Protocol "peer does not support Extended Main Secret" HandshakeFailure)))
Error: processing vignette 'sample-scripts-external-genotype-simulation.Rmd' failed with diagnostics:
pandoc document conversion failed with error 61
--- failed re-building ‘sample-scripts-external-genotype-simulation.Rmd’

SUMMARY: processing the following files failed:
  ‘Simulation-and-LinearModel.Rmd’ ‘SimulationBasedOnExampleData.Rmd’
  ‘sample-scripts-external-genotype-simulation.Rmd’

Error: Vignette re-building failed.
Execution halted