Found the following significant warnings:

  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
Deprecated functions may be defunct as soon as of the next release of
R.
See ?Deprecated.
Examples with CPU (user + system) or elapsed time > 5s
                                           user system elapsed
MinimalInformative                        7.633  0.083  12.449
examine                                   6.053  0.052  10.476
stopTrial                                 4.825  0.020   8.269
show-PseudoDualSimulationsSummary-method  4.748  0.055   7.334
plot-PseudoDualSimulations-missing-method 4.498  0.003   6.428
summary-PseudoDualSimulations-method      4.389  0.004   5.809
plot-SimulationsSummary-missing-method    3.554  0.008   5.936
nextBest                                  3.168  0.044   5.525
simulate-DualDesign-method                2.971  0.008   5.038
show-SimulationsSummary-method            2.942  0.025   5.006
summary-Simulations-method                2.720  0.004   5.031