Found the following significant warnings:

  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
  Warning: 'is.R' is deprecated.
Deprecated functions may be defunct as soon as of the next release of
R.
See ?Deprecated.
Examples with CPU (user + system) or elapsed time > 5s
           user system elapsed
tvt.eSIR2 6.126  0.024   8.310
tvt.eSIR  5.782  0.027   7.062
eSAIR     5.340  0.044   6.547
qh.eSIR   5.350  0.029   6.234