Error(s) in re-building vignettes:
--- re-building 'Tutorial.Rmd' using rmarkdown


Warning: unable to access index for repository https://bioconductor.org/packages/3.14/bioc/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/bioc/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/annotation/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/annotation/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/experiment/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/experiment/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/workflows/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/workflows/src/contrib/PACKAGES'
Bioconductor version 3.14 (BiocManager 1.30.19), R 4.1.3 (2022-03-10)
Installing package(s) 'BiocVersion', 'leukemiasEset'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/bioc/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/bioc/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/annotation/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/annotation/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/experiment/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/experiment/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/workflows/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/workflows/src/contrib/PACKAGES'
Warning: packages 'BiocVersion', 'leukemiasEset' are not available for Bioconductor version '3.14'

Versions of these packages for your version of R might be available elsewhere,
see the ideas at
https://cran.r-project.org/doc/manuals/r-patched/R-admin.html#Installing-packages
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/bioc/bin/windows/contrib/4.1:
  cannot open URL 'https://bioconductor.org/packages/3.14/bioc/bin/windows/contrib/4.1/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/annotation/bin/windows/contrib/4.1:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/annotation/bin/windows/contrib/4.1/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/experiment/bin/windows/contrib/4.1:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/experiment/bin/windows/contrib/4.1/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/workflows/bin/windows/contrib/4.1:
  cannot open URL 'https://bioconductor.org/packages/3.14/workflows/bin/windows/contrib/4.1/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/bioc/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/bioc/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/annotation/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/annotation/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/data/experiment/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/data/experiment/src/contrib/PACKAGES'
Warning: unable to access index for repository https://bioconductor.org/packages/3.14/workflows/src/contrib:
  cannot open URL 'https://bioconductor.org/packages/3.14/workflows/src/contrib/PACKAGES'
Installation paths not writeable, unable to update packages
  path: D:/RCompile/recent/R-4.1.3/library
  packages:
    MASS, Matrix, boot, cluster, foreign, mgcv, nlme, nnet, rpart, survival
Old packages: 'stringi'
Quitting from lines 131-144 (Tutorial.Rmd) 
Error: processing vignette 'Tutorial.Rmd' failed with diagnostics:
there is no package called 'leukemiasEset'
--- failed re-building 'Tutorial.Rmd'

SUMMARY: processing the following file failed:
  'Tutorial.Rmd'

Error: Vignette re-building failed.
Execution halted