Running examples in 'directPA-Ex.R' failed
The error most likely occurred in:

> ### Name: directPA
> ### Title: Direction Analysis for Pathways
> ### Aliases: directPA
> 
> ### ** Examples
> 
> 
> # load the proteomics dataset
> data(PM)
> 
> # load pathway annotations
> data(Pathways)
> 
> # display reactome pathways. Could be replaced by any other pathway databases
> Pathways.reactome[1:5]
$REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS
 [1] "AGL"       "GYG1"      "PGM1"      "PHKA1"     "PHKA2"     "PHKB"     
 [7] "PHKG1"     "PHKG2"     "PGM2"      "PYGB"      "PYGL"      "PYGM"     
[13] "PHKA1P1"   "LOC650556" "CALM1"     "CALM2"     "CALM3"     "GYG2"     

$REACTOME_TRANSLATION
  [1] "SEC61B"    "RPL35"     "EEF1DP1"   "RPL7AP27"  "DDOST"     "EEF1A1"   
  [7] "EEF1B2"    "EEF1D"     "EEF1G"     "EEF2"      "EIF1AX"    "EIF2S1"   
 [13] "EIF2B1"    "EIF2S3"    "EIF4A1"    "EIF4A2"    "EIF4B"     "EIF4E"    
 [19] "EIF4EBP1"  "EIF4G1"    "EIF5"      "ETF1"      "FAU"       "TRAM1"    
 [25] "SEC11A"    "SEC61G"    "RPL13A"    "GSPT2"     "RPL36"     "PABPC1"   
 [31] "EIF3K"     "RPL10P16"  "FAM153A"   "SPCS1"     "SEC61A1"   "EIF3FP3"  
 [37] "RPL36P14"  "EIF3E"     "RPSAP12"   "RPS8P10"   "RPL7AP66"  "RPL10P9"  
 [43] "RPS12P4"   "RPSA"      "RPS26P10"  "RPL23AP2"  "RPS12P22"  "RPL21P29" 
 [49] "RPS26P35"  "RPL10A"    "RPL26L1"   "SEC61A2"   "SRPRB"     "SPCS3"    
 [55] "RPL3"      "RPL3L"     "RPL4"      "RPL5"      "RPL6"      "RPL7"     
 [61] "RPL7A"     "RPL8"      "RPL9"      "RPL10"     "RPL11"     "RPL12"    
 [67] "RPL13"     "RPL15"     "RPL17"     "RPL18"     "RPL18A"    "RPL19"    
 [73] "RPL21"     "RPL22"     "RPL23A"    "RPL24"     "RPL26"     "RPL27"    
 [79] "RPL30"     "RPL27A"    "RPL28"     "RPL29"     "RPL31"     "RPL32"    
 [85] "RPL34"     "RPL35A"    "RPL37"     "RPL37A"    "RPL38"     "RPL39"    
 [91] "RPL41"     "RPL36A"    "RPLP0"     "RPLP1"     "RPLP2"     "RPN1"     
 [97] "RPN2"      "RPS2"      "RPS3"      "RPS3A"     "RPS4X"     "RPS4Y1"   
[103] "RPS5"      "RPS6"      "RPS7"      "RPS8"      "RPS9"      "RPS10"    
[109] "RPS11"     "RPS12"     "RPS13"     "RPS14"     "RPS15"     "RPS15A"   
[115] "RPS16"     "RPS17"     "RPS18"     "RPS19"     "RPS20"     "RPS21"    
[121] "RPS23"     "RPS24"     "RPS25"     "RPS26"     "RPS27"     "RPS27A"   
[127] "RPS28"     "RPS29"     "RPL6P19"   "LOC647030" "LOC641895" "RPL36AP31"
[133] "RPS29P3"   "RPS26P28"  "RPL36AP8"  "RPL26P22"  "RPS26P20"  "RPS15AP11"
[139] "RPS26P50"  "RPL22P11"  "RPL17P6"   "RPS13P8"   "RPS28P4"   "RPL32P16" 
[145] "LOC646184" "RPS28P7"   "RPL12P2"   "LOC647074" "RPL23AP42" "RPL5P1"   
[151] "RPL36AP51" "LOC649602" "LOC650638" "RPS28P9"   "RPL34P27"  "LOC651825"
[157] "LOC651894" "LOC652607" "RPL26P30"  "RPSAP9"    "SRP9P1"    "RPL19P9"  
[163] "LOC653566" "RPL21P119" "RPL31P17"  "LOC653881" "LOC653994" "SRP9"     
[169] "SRP14"     "SRP19"     "SRP54"     "SRP68"     "SRP72"     "SRPR"     
[175] "SSR1"      "SSR2"      "SSR3"      "SSR4"      "RPL31P31"  "RPL15P17" 
[181] "RPL23AP18" "RPL26P24"  "RPL21P75"  "RPS27AP11" "RPS26P7"   "RPL21P134"
[187] "RPS26P25"  "RPS19P3"   "RPL36AP23" "RPS18P10"  "RPL17P36"  "RPL36AP37"
[193] "RPL21P16"  "RPL23AP74" "RPS15P5"   "RPL23AP63" "LOC729998" "RPS10P9"  
[199] "LOC730343" "RPS18P5"   "UBA52"     "RPL34P31"  "EIF4H"     "EIF3A"    
[205] "EIF3B"     "EIF3C"     "EIF3D"     "EIF3F"     "EIF3G"     "EIF3H"    
[211] "EIF3I"     "EIF3J"     "EIF2B4"    "EIF2B3"    "EIF2B2"    "EIF2B5"   
[217] "EIF2S2"    "RPL14"     "SEC11C"    "RPL23"     "EIF5B"     "SPCS2"    

$REACTOME_PYRIMIDINE_CATABOLISM
 [1] "UPP2"   "DPYD"   "DPYS"   "TYMP"   "NT5C"   "NT5E"   "NT5C3"  "UPB1"  
 [9] "NT5M"   "AGXT2"  "UPP1"   "NT5C1A"

$REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER
 [1] "POLR3F"  "POLR3C"  "POLR3A"  "LZTS1"   "POLR3H"  "BRF1"    "GTF3C2" 
 [8] "POLR1D"  "POLR3K"  "POLR2E"  "POLR2F"  "POLR2H"  "POLR2K"  "POLR2L" 
[15] "POLR3B"  "POLR3E"  "POLR3D"  "TBP"     "POLR3GL" "GTF3C5"  "GTF3C4" 
[22] "GTF3C3"  "POLR1C" 

$REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS
 [1] "ANAPC10"   "UBE2C"     "CDC26"     "ANAPC2"    "ANAPC4"    "MAD2L1"   
 [7] "ANAPC5"    "ANAPC7"    "ANAPC11"   "ANAPC1"    "LOC647654" "LOC649620"
[13] "LOC650621" "LOC651763" "BUB1B"     "CDC26P1"   "LOC730594" "UBE2D1"   
[19] "UBE2E1"    "CDC23"     "CDC16"     "BUB3"      "CDC20"     "CDC27"    

> 
> # direction pathway analysis in 3-dimensional space. Implemnted as rotating by contrast
> # (1) test combined effect of all 3 treatments (stimulation and inhibitions) vs control (basal) 
> # on the original direction.
> dPA <- directPA(Tc=PM, direction=c(1,1,1), annotation=Pathways.reactome)
Error in library.dynam(lib, package, package.lib) : 
  DLL 'rlang' not found: maybe not installed for this architecture?
Calls: directPA ... loadNamespace -> namespaceImport -> loadNamespace -> library.dynam
Execution halted