Error(s) in re-building vignettes:
--- re-building ‘get_sarted_with_mutSignatures.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) not available. Falling back to R Markdown v1.
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in axis(if (horiz) 1 else 2, cex.axis = cex.axis, ...) :
  no font could be found for family "Arial"
Warning in graphics::title(ylab = "Iter. Results (by Group)", line = 1,  :
  no font could be found for family "Arial"
Warning in graphics::title(ylab = "Iter. Results (by Group)", line = 1,  :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in title(main = main, sub = sub, xlab = xlab, ylab = ylab, ...) :
  no font could be found for family "Arial"
Warning in graphics::axis(side = 1, tick = FALSE, hadj = 1, cex.axis = xaxis_cex,  :
  no font could be found for family "Arial"
Warning in graphics::axis(side = 2, tick = -0.005, at = my.y, labels = my.y.labs,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(names.first.out, side = 1, line = 1.5, at = lab.xx,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(xlab, side = 1, line = 3, at = base::mean(xpos[,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(xlab, side = 1, line = 3, at = base::mean(xpos[,  :
  no font could be found for family "Arial"
Warning in graphics::mtext(xlab, side = 1, line = 3, at = base::mean(xpos[,  :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in doTryCatch(return(expr), name, parentenv, handler) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_stringMetric, as.graphicsAnnot(x$label)) :
  no font could be found for family "Arial"
Warning in grid.Call(C_textBounds, as.graphicsAnnot(x$label), x$x, x$y,  :
  no font could be found for family "Arial"
Quitting from lines 282-303 (get_sarted_with_mutSignatures.Rmd) 
Error: processing vignette 'get_sarted_with_mutSignatures.Rmd' failed with diagnostics:
polygon edge not found
--- failed re-building ‘get_sarted_with_mutSignatures.Rmd’

SUMMARY: processing the following file failed:
  ‘get_sarted_with_mutSignatures.Rmd’

Error: Vignette re-building failed.
Execution halted