Error(s) in re-building vignettes:
  ...
--- re-building ‘about.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘about.Rmd’

--- re-building ‘case-1-pleiotropy.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
Quitting from lines 246-272 (case-1-pleiotropy.Rmd) 
Error: processing vignette 'case-1-pleiotropy.Rmd' failed with diagnostics:
Bad Gateway (HTTP 502).
Detail:
{html_document}
<html>
[1] <head>\n<meta http-equiv="Content-Type" content="text/html; charset=UTF-8 ...
[2] <body>\n<h1>Proxy Error</h1>\n<p>The proxy server received an invalid\r\n ...do.call(method, args = list(route = route, params = params, retry_times = retry_times, retry_pause_min = retry_pause_min, call = call))
--- failed re-building ‘case-1-pleiotropy.Rmd’

--- re-building ‘case-2-alt-drug-target.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘case-2-alt-drug-target.Rmd’

--- re-building ‘case-3-literature-triangulation.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
Quitting from lines 204-217 (case-3-literature-triangulation.Rmd) 
Error: processing vignette 'case-3-literature-triangulation.Rmd' failed with diagnostics:
Unknown colour name: c("orch", "phsu")
--- failed re-building ‘case-3-literature-triangulation.Rmd’

--- re-building ‘meta-functionalities.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘meta-functionalities.Rmd’

--- re-building ‘options.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘options.Rmd’

--- re-building ‘using-epigraphdb-api.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘using-epigraphdb-api.Rmd’

--- re-building ‘using-epigraphdb-r-package.Rmd’ using rmarkdown
Warning in engine$weave(file, quiet = quiet, encoding = enc) :
  Pandoc (>= 1.12.3) and/or pandoc-citeproc not available. Falling back to R Markdown v1.
--- finished re-building ‘using-epigraphdb-r-package.Rmd’

SUMMARY: processing the following files failed:
  ‘case-1-pleiotropy.Rmd’ ‘case-3-literature-triangulation.Rmd’

Error: Vignette re-building failed.
Execution halted