Error(s) in re-building vignettes:
--- re-building ‘AUC-Calculation-with-PKNCA.Rmd’ using rmarkdown
Loading required namespace: ggplot2
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'AUC-Calculation-with-PKNCA.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘AUC-Calculation-with-PKNCA.Rmd’

--- re-building ‘Data-Cleaning-in-PKNCA.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Data-Cleaning-in-PKNCA.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Data-Cleaning-in-PKNCA.Rmd’

--- re-building ‘Example-theophylline.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Example-theophylline.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Example-theophylline.Rmd’

--- re-building ‘Introduction-and-Usage.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Introduction-and-Usage.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Introduction-and-Usage.Rmd’

--- re-building ‘Methods-for-Dose-Aware-Interpolation-and-Extrapolation.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Methods-for-Dose-Aware-Interpolation-and-Extrapolation.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Methods-for-Dose-Aware-Interpolation-and-Extrapolation.Rmd’

--- re-building ‘Options-for-Controlling-PKNCA.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Options-for-Controlling-PKNCA.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Options-for-Controlling-PKNCA.Rmd’

--- re-building ‘PKNCA-validation.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'PKNCA-validation.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘PKNCA-validation.Rmd’

--- re-building ‘Selection-of-Calculation-Intervals.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Selection-of-Calculation-Intervals.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Selection-of-Calculation-Intervals.Rmd’

--- re-building ‘Superposition.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Superposition.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Superposition.Rmd’

--- re-building ‘Writing-Parameter-Functions.Rmd’ using rmarkdown
dyld: lazy symbol binding failed: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

dyld: Symbol not found: ____chkstk_darwin
  Referenced from: /usr/local/bin/pandoc (which was built for Mac OS X 10.15)
  Expected in: /usr/lib/libSystem.B.dylib

Error: processing vignette 'Writing-Parameter-Functions.Rmd' failed with diagnostics:
pandoc document conversion failed with error 6
--- failed re-building ‘Writing-Parameter-Functions.Rmd’

SUMMARY: processing the following files failed:
  ‘AUC-Calculation-with-PKNCA.Rmd’ ‘Data-Cleaning-in-PKNCA.Rmd’
  ‘Example-theophylline.Rmd’ ‘Introduction-and-Usage.Rmd’
  ‘Methods-for-Dose-Aware-Interpolation-and-Extrapolation.Rmd’
  ‘Options-for-Controlling-PKNCA.Rmd’ ‘PKNCA-validation.Rmd’
  ‘Selection-of-Calculation-Intervals.Rmd’ ‘Superposition.Rmd’
  ‘Writing-Parameter-Functions.Rmd’

Error: Vignette re-building failed.
Execution halted