Running examples in ‘phase1RMD-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: plot.RunRMDVal
> ### Title: plot nTTP Toxicity-based in cycle 1 for all doses.
> ### Aliases: plot.RunRMDVal
> 
> ### ** Examples
> 
> # Setup the prior distributions for the phase I dose-finding model:
> control <- list(
+  beta.dose = parm("normal", mean = 0, var = 1000),
+  beta.other = parm("normal", mean = 0, var = 1000 ),
+  gamma = parm("normal", mean = 0, var = 100 ),
+  s2.gamma = parm("invgamma", shape = 0.001, scale = 0.001),
+  s2.epsilon = parm("invgamma", shape = 0.001, scale = 0.001)
+  )
>  
> # Load the example patient toxicity data:
> data(patdata)
> 
> # Estimate the dose-recommendation of the next patient cohort based on the toxicity data:
> res <- RunRMD(data=patdata, control=control, tox.target=0.28, 
+   iter=2000, burnin=500, thin=1, chains=1)
Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in vector-array arithmetic is deprecated.
  Use c() or as.vector() instead.

Warning in mu + rnorm(ncol(X.dose) * 1000)/U :
  Recycling array of length 1 in array-vector arithmetic is deprecated.
  Use c() or as.vector() instead.


Model: RMD with longitudinal toxicity

Doses (skeleton):
[1] 1 2 3 4 5 6

The maximum sample size is: 36
Posterior estimates (mean) of toxicity:
       Dose 1 Dose 2 Dose 3 Dose 4 Dose 5 Dose 6
toxpf1  0.068  0.235  0.402  0.569  0.736  0.904
toxpf2  0.135  0.303  0.470  0.636  0.803  0.970
toxpf3  0.203  0.370  0.537  0.704  0.870  1.038
toxpf4  0.269  0.438  0.604  0.771  0.938  1.105
toxpf5  0.337  0.505  0.670  0.838  1.005  1.172
toxpf6  0.404  0.571  0.738  0.905  1.072  1.240

Next recommended dose: 2
> 
> plot(res);
Error in grid.Call.graphics(C_setviewport, vp, TRUE) : 
  VECTOR_ELT() can only be applied to a 'list', not a 'double'
Calls: <Anonymous> ... lapply -> FUN -> push.vp.viewport -> grid.Call.graphics
Execution halted