* using log directory ‘/Volumes/Builds/packages/big-sur-arm64/results/4.3/dnapath.Rcheck’ * using R version 4.3.0 beta (2023-04-07 r84200) * using platform: aarch64-apple-darwin20 (64-bit) * R was compiled by Apple clang version 14.0.0 (clang-1400.0.29.202) GNU Fortran (GCC) 12.2.0 * running under: macOS Big Sur 11.6.7 * using session charset: UTF-8 * checking for file ‘dnapath/DESCRIPTION’ ... OK * checking extension type ... Package * this is package ‘dnapath’ version ‘0.7.4’ * package encoding: UTF-8 * checking package namespace information ... OK * checking package dependencies ... NOTE Packages suggested but not available for checking: 'GENIE3', 'reactome.db' * checking if this is a source package ... OK * checking if there is a namespace ... OK * checking for executable files ... OK * checking for hidden files and directories ... OK * checking for portable file names ... OK * checking for sufficient/correct file permissions ... OK * checking whether package ‘dnapath’ can be installed ... [11s/12s] OK See 'https://www.r-project.org/nosvn/R.check/r-oldrel-macos-arm64/dnapath-00install.html' for details. * used C++ compiler: ‘Apple clang version 13.0.0 (clang-1300.0.29.30)’ * used SDK: ‘MacOSX11.3.sdk’ * checking C++ specification ... NOTE Specified C++11: please drop specification unless essential * checking installed package size ... OK * checking package directory ... OK * checking ‘build’ directory ... OK * checking DESCRIPTION meta-information ... OK * checking top-level files ... OK * checking for left-over files ... OK * checking index information ... OK * checking package subdirectories ... OK * checking R files for non-ASCII characters ... OK * checking R files for syntax errors ... OK * checking whether the package can be loaded ... [1s/1s] OK * checking whether the package can be loaded with stated dependencies ... [1s/1s] OK * checking whether the package can be unloaded cleanly ... 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[9s/9s] ERROR Running examples in ‘dnapath-Ex.R’ failed The error most likely occurred in: > ### Name: run_genie3 > ### Title: Wrapper for GENIE3 method > ### Aliases: run_genie3 > > ### ** Examples > > if(!requireNamespace("GENIE3", quietly = TRUE)) { + data(meso) + data(p53_pathways) + + # To create a short example, we subset on two pathways from the p53 pathway list, + # and will only run 5 permutations for significance testing. + pathway_list <- p53_pathways[c(8, 13)] + n_perm <- 5 + + # Use this method to perform differential network analysis. + # The parameters in run_genie3() can be adjusted using the ... argument. + # For example, the 'nTrees' parameter can be specified as shown here. + results <- dnapath(x = meso$gene_expression, + pathway_list = pathway_list, + group_labels = meso$groups, + n_perm = n_perm, + network_inference = run_genie3, + nTrees = 100) + summary(results) + + # The group-specific association matrices can be extracted using get_networks(). + nw_list <- get_networks(results[[1]]) # Get networks for pathway 1. + + # nw_list has length 2 and contains the inferred networks for the two groups. + # The gene names are the Entrezgene IDs from the original expression dataset. + # Renaming the genes in the dnapath results to rename those in the networks. + # NOTE: The temporary directory, tempdir(), is used in this example. In practice, + # this argument can be removed or changed to an existing directory + results <- rename_genes(results, to = "symbol", species = "human", + dir_save = tempdir()) + nw_list <- get_networks(results[[1]]) # The genes (columns) will have new names. + + # (Optional) Plot the network using SeqNet package (based on igraph plotting). + # First rename entrezgene IDs into gene symbols. + SeqNet::plot_network(nw_list[[1]]) + } Warning: The `GENIE3` package must be installed to use run_genie3(). Using run_corr() instead. Error in wCorr::weightedCorr(x[, index_set[1, i]], x[, index_set[2, i]], : The vectors ‘x’, ‘y’, and ‘weights’ must all be of the same length. Calls: dnapath ... network_inference -> run_corr -> sapply -> lapply -> FUN -> Execution halted * checking for unstated dependencies in ‘tests’ ... OK * checking tests ... [4s/4s] OK Running ‘testthat.R’ [4s/4s] * checking for unstated dependencies in vignettes ... OK * checking package vignettes in ‘inst/doc’ ... OK * checking running R code from vignettes ... [0s/0s] NONE ‘introduction_to_dnapath.Rmd’ using ‘UTF-8’... [0s/0s] OK ‘package_data.Rmd’ using ‘UTF-8’... [0s/0s] OK * checking re-building of vignette outputs ... [25s/55s] OK * checking PDF version of manual ... [5s/5s] OK * DONE Status: 1 ERROR, 3 NOTEs * using check arguments '--no-clean-on-error ' * elapsed time (check, wall clock): 1:57